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Description

GA120010: H-Ser(Gal(β(1-3)GalNAc)-OHC17H30N2O13 470. 43 A fully unprotected (free amine, free acid) L serine glycoamino acid carrying a Gal1 3GalNAc disaccharide. This deprotected building block is suited to use as a reference standard, an enzymatic substrate acceptor, or for conjugation and analytical work rather than direct Fmoc SPPS. The installed glycan is the T antigen core 1 structure (Gal1 3GalNAc O Ser Thr), a tumor associated carbohydrate antigen and ligand for galectins and

β-D-Lac-Butyl-Carboxylic Acid

Fmoc-Thr(beta-D-Cel)-OH (Peracetate)

/ Fmoc-Thr((Ac)7-Cel-β-D)-OH / Fmoc-Thr(β-D-Cel)-OH (Peracetate)

3-Aminopropyl [(5-acetamido-3

with the natural Thr presentation of mucin-type O-glycans

β-D-Glc-Butyl-Carboxylic Acid

6-(2-Acetamido-2-deoxy-β-D-Galactopyranosyl-oxy) hexanoic acid

R) / α-Tocopherol-d6 (R

Fmoc-L-Thr((Ac)3-Fuc-α-L)-OH

22 / A β-D-glucose ligand equipped with an azide-functionalized linker through a short ethyl spacer

/ α-D-Man-Ethyl-Amine / α-Man-Et-NH2

4-Nitrophenyl (pNP) glycosides are chromogenic enzyme substrates: cleavage of the glycosidic bond by the target enzyme releases free 4-nitrophenol