BT000070: Neu5Acα(2-6)GalNAc-α-Thr-NH-Biotin

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Description

BT000070: Neu5Acα(2-6)GalNAc-α-Thr-NH-BiotinC33H53N5O18S 839. 86 A sialyl Tn antigen (Neu5Ac2 6GalNAc) on a threonine residue equipped with a biotin tag through an amide bond. The biotin moiety binds with high affinity to streptavidin and neutravidin, enabling straightforward immobilization on chips, in wells, or on other streptavidin neutravidin coated platforms. This compound presents the sialyl Tn antigen (Neu5Ac2 6GalNAc) on a threonine residue, a tumor associated carbohydrate antigen and

N-α-Fmoc-O-β-(2-acetamido-2-deoxy-3

4-Carboxybutyl N-acetyl-α-D-galactosamine

It is also relevant to O-GlcNAc and N-glycan biosynthesis research and serves as a substrate for galactosyltransferases and other glycosyltransferases

/ α-D-Man-Ethyl-Thiol / α-Man-Et-SH

This deprotected building block is suited to use as a reference standard

C18H32N2O13 / 484

47 / A β-D-N-acetylgalactosamine (GalNAcβ) ligand equipped with an amine-functionalized linker through a pentyl spacer

N-Biotin-Thr(Galβ(1-3)GalNAc-α)-OH

6) Asn-PEG8-Biotin (extended tri-LacNAc arms)

C14H25NO8 / 335

/ β-D-Glc-Ethyl-Amine / β-Glc-Et-NH2

providing a straightforward route to conjugate the glycan onto NHS-activated molecules and surfaces

Exchange/Return Notes