PE234005: β-GlcNAc-PEG3-Azide (Peracetate)

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Description

PE234005: β-GlcNAc-PEG3-Azide (Peracetate)C20H32N4O11 504. 49 A peracetylated D N acetylglucosamine (GlcNAc) ligand equipped with an azide handle through a hydrophilic PEG3 spacer. The terminal azide couples to alkynes via copper catalyzed azide alkyne cycloaddition (CuAAC) or to DBCO and related strained alkynes via copper free click chemistry, forming stable 1,2,3 triazole linkages. The sugar hydroxyls are acetate protected to increase lipophilicity for cell membrane permeability. This

R) / α-Tocopherol-d3 Acetate

(β-D-GalNAc-sp)3-NHC(O)-PEG3-N3

/ β-D-GalNAc-Pentyl-Amine (Boc protected) / β-D-GalNAc-Pe-NH-Boc

/ α-D-Man-Butyl-Carboxylic Acid / α-Man-Bu-CO2H

Fmoc-Ser(β-D-Cellibiose)-OH (Peracetate)

C31H54N2O21S / 822

Applications include: Metabolic studies

33 / Anti-Epileptic / rac-Brivaracetam-d7 / (2S)-2-[(4R)-2-oxo- 4-propylpyrrolidin-1-yl] butanamide-d7

Fmoc-Ser(β-L-Fuc(Ac)3)-OH

/ β-Gal-PEG3-Azide (Peracetate) / N/A

6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-L-threonine

5-Trihydroxy-6-[1-(isopropylamino-methyl)-2-(naphthalen-1-yloxy)-ethoxy]-tetrahydro-pyran-2-carboxylic acid